Location Matters: Synaptotagmin Helps Place Vesicles Near Calcium Channels

نویسندگان

  • Benjamin D. McNeil
  • Ling-Gang Wu
چکیده

Positioning releasable vesicles near voltage-gated calcium channels may ensure transmitter release upon calcium influx. Disruption of vesicle positioning may underlie short-term synaptic depression. However, how this positioning is achieved is unclear. In this issue of Neuron, Young and Neher find that synaptotagmin 2 helps to align readily releasable vesicles near calcium channels at nerve terminals.

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عنوان ژورنال:
  • Neuron

دوره 63  شماره 

صفحات  -

تاریخ انتشار 2009